I have had lupus for 32 years. 10 years ago, I was prescribed methotrexate In tablet format. It caused so many side effects, diarrhea, vomiting and hair loss, to name a few. They took me off it. Now I have a very itchy rash all over my face, neck and arms. I have a new dermatologist who is trying to convince me that if I take methotrexate in injection form, it will improve my skin with fewer side effects. I'm not sure. Has anyone had experience with side effects or skin improvement with injections?