A B-3 vitamin variant

By JMG1

1 min read

I joined this forum because of the benefits of taking a variant in the B-3 vitamin group that my friend had a good experience with. The vitamin is "nicotinamide riboside (NR), a water soluable B-3, and my friend said they had no side effects. It has been given GRAS status by the NIH FDA. It is the best precursor of NAD, a co-enzyme in all cells. Raising NAD levels is beneficial to metabolism and for people with lupus. I suggest the following internet searches: 1. "NAD and lupus". 2. Nicotinamide Riboside and lupus. 3. RaisingNAD.com 4. AboutNAD.com

Have you had experiences using vitamins to help alleviate lupus-related symptoms? Tell us in the comments

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GabbyFormica Community Admin
So glad that your friend found this helpful in their lupus journey! It's important to remember that everyone's body reacts differently to different treatments and no two lupus journeys are the same. Remember to talk to your doctor before starting any new treatments of any kind! Gabby (team member)
JMG1 Member
While I would never recommend not taking with a doctor, I suggest printing out some of the research that you find on-line and providing it to her or him. None of my physician friends have heard of it, and many are reluctant to believe a vitamin that they haven't heard of as being efficacious. I would include the information about it having NIH GRAS recognition from the NIH FDA. BTW: The normal source of it, in limited quantities, is manufactured in the body in unprocessed vegetables, fish, and other whole foods. In pure direct state, we got NR in mother's milk as infants. I have not seen it in capsules greater than 300 mg, but I take 900 mg per day. It has been tested as safe to at least 1,000 mg per day, and many trials on <a href='https://clinicaltrials.gov' target='_blank' rel='noopener noreferrer ugc'>clinicaltrials.gov</a> use 2,000 mg per day. That few people or their doctors have heard of it is possibly because it is much less expensive than prescription medications. As I understand, big pharmaceutical companies have not shown an interest in it because it is not worth the great cost to have it classified as a drug, since even a triple dose, as I take, costs less than $100 per month.
1. GabbyFormica Community Admin
 <inline-mention username="JMG1" user-id="4496081"/>, Glad you found something that works for you. It's always important to check with your doctor when you are seeking supportive lupus treatments, but I appreciate your suggestion to bring in some information to review with your doctor as well! It's a team effort! Are you or someone you care about living with lupus and using this vitamin to help ease their symptoms? Gabby (team member)
JMG1 Member
I had told a friend with chemo-induced neuropathy about the B-3 nicotinamide riboside (NR). He experienced very dramatic positive results, even at 300 mg, and increased 600 mg. It took about 2 months for the full benefits to be realized. He told his in-laws about it. His s sister-in-law has lupus. She started taking it, and also at about two months, experienced great improvement regarding her symptoms. At the time I was unfamiliar with the potential of NR regarding lupus, but I now understand that it shows great potential regarding metabolic diseases generally. The reason is that in many metabolic conditions the co-enzyme NAD (nicotinamide adenine dineucleotide) is challenged and in limited supply. NR restores NAD. I should add that a glycol-protein, CD-38, inhibits NAD. CD-38 is controlled by various molecules, especially apigenin and quercetin. Eating a lot of parsley or drinking a lot of chamomile tea can help in this regard. Other natural sources include apples, orangesebc, but perhaps not in therapeutic quantities to be effective with lupus. The supplemental form of quercetin (found in blueberries) is easier to find than apigenin. Readers here should do research beyond what I have written. I suggest combining searches with: nicotinamide riboside, nicotinamide adenine dineucleotide, lupus, metabolic disease etc. They will find a lot of research has and is being conducted. I should add that I recently saw an advertisement for a product that included NR. It said, "Feel like a Kid Again", and showed an older dad or grandpa playing with a young child. At age 71, I think I feel like I did when I was 45, and much younger feeling than I did at 55. Without having experienced it, I would have dismissed the advertisement being a false claim. Among the many trials ongoing with NR is at least one regarding psoriasis a metabolic disease as I understand. I have (had) a mild form, and now my elbows, feet and one knee are completely clear of it, with one knee has just a hint of it